The effect of Bumethanide treatment on seizure controlling in patients with drug resistance temporal lobe epilepsies candidate for surgery
Phase 1
- Conditions
- Temporal Lobe Epilepsy.other epilepsy
- Registration Number
- IRCT201012115368N1
- Lead Sponsor
- Cellular and Molecular Research Center of Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 5
Inclusion Criteria
Inclusion: 1) Suffering from drug resistance temporal lobe epilepsy 2) Candidate for temporal lobectomy 3) Giving informed consent.
Exclusion: Contraindication for Bumethanide
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Seizure occurrence. Timepoint: 1 month before and 1 month after intervention. Method of measurement: EEG.
- Secondary Outcome Measures
Name Time Method Dose reduction of anti-epileptic drugs. Timepoint: 3 months before and 3 months after intervention. Method of measurement: dosage.