EUCTR2008-006947-38-GB
进行中(未招募)
1 期
A randomised double-blind placebo-controlled pilot study of D-cycloserine-augmented exposure therapy in adolescents with obsessive-compulsive disorder
King's College London (Institute of Pyschiatry)0 个研究点目标入组 24 人2009年7月9日
相关药物Cycloserine
概览
- 阶段
- 1 期
- 干预措施
- 未指定
- 疾病 / 适应症
- 未指定
- 发起方
- King's College London (Institute of Pyschiatry)
- 入组人数
- 24
- 状态
- 进行中(未招募)
- 最后更新
- 7年前
概览
简要总结
暂无简介。
研究者
入排标准
入选标准
- •i) DSM\-IV diagnosis of OCD
- •ii) Age 12\-18
- •iii) Referred to the National and Specialist OCD clinic at Maudsley Hospital
- •iv) If on medication, that should be stable for 12 weeks, and not be changed during the course of the trial
- •v) Provision of written informed consent (patient and carer)
- •Are the trial subjects under 18? yes
- •Number of subjects for this age range:
- •F.1\.2 Adults (18\-64 years) yes
- •F.1\.2\.1 Number of subjects for this age range
- •F.1\.3 Elderly (\>\=65 years) no
排除标准
- •i) Current diagnosis of psychosis, current alcohol or substance abuse/dependence
- •ii) English too poor to engage in treatment
- •iii) Severe disabling neurological disorder
- •iv) Medical contraindication to cycloserine, including epilepsy and porphyria
- •v) A diagnosed global learning disability or pervasive developmental disorder
- •vi) Characteristics interfering with completion of treatment eg life\-threatening or unstable medical illness
- •vii) Pregnancy
- •viii) Not suitable for CBT (selective mutism, lack of insight or motivation to change)
结局指标
主要结局
未指定
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