ChiCTR2100053912招募中Unknown
Can whole-body vibration treatment optimize cognitive function in older adults who have sarcopenia and are at risk of dementia: A randomized controlled trial.
Health and Medical Research Fund1 个研究点 分布在 1 个国家目标入组 156 人开始时间: 2021年12月17日最近更新:
适应症
试验速览
- 阶段
- Unknown
- 状态
- 招募中
- 发起方
- 入组人数
- 156
- 试验地点
- 1
- 主要终点
- Global cognitive function
研究概览
简要总结
The objective is to ascertain if vibration treatment optimizes cognitive function in older adults who have sarcopenia and are at risk of dementia.
研究设计
- 研究类型
- Interventional
- 主要目的
- 随机平行对照
- 盲法
- None
入排标准
- 年龄范围
- 60 至 100（—）
- 性别
- All
入选标准
- •Community-living Chinese individuals aged 60 or older with sarcopenia but without clinical dementia will be recruited from local elderly centres equipped with our vibration platform, V-Health. All individuals will be screened at our research centre (the Orthopaedic Learning Centre) for the following:
- •presence of sarcopenia, defined according to the latest diagnostic criteria published by the Asian Working Group of Sarcopenia (AWGS):
- •(1) hand-grip strength (male at < 28kg; female at < 18kg),
- •(2) 6-metre gait speed test (< 1.0m/s), and
- •(3) height-adjusted skeletal muscle mass measured by dual-energy X-ray absorptiometry (DXA, male at <7.0kg/m2 and female at < 5.4kg/m2), defined by appendicular skeletal muscle mass/height2
- •at risk of dementia, according to age- and education-matched cutoff of the Hong Kong Chinese version of Montreal Cognitive Assessment (HK-MoCA);
- •being able to stand independently without any aids; and
- •not receiving vibration treatment in the past 1 year.
排除标准
- •include non-Chinese ethnicity; living in care homes; having history of dementia, stroke, traumatic brain injury, epilepsy, or Parkinsons disease; taking drugs that affect cognition (benzodiazepines, anti-dementia medication, etc.); having history of severe mental illness (SMI), including bipolar affective disorder and schizophrenia, or substance abuse; already attending other cognitive intervention programs; significant impairments in communication; having any hormonal replacement therapy or drug treatment that could affect normal metabolism of musculoskeletal system; having any hypo- or hyperparathyroidism, renal, liver, or chronic inflammatory conditions known to affect muscle metabolism; having pacemaker or implant in situ; having difficulty in standing independently; and already having regular vibration treatment.
研究组 & 干预措施
Control group
12-week observation, followed by 12-week vibration intervention
Experimental group
12-week vibration intervention, followed by 12-week observation
结局指标
主要结局
Global cognitive function
次要结局
- Cognitive domains
- Efficiency of brain network
研究者
研究点 (1)
Loading locations...
相似试验
尚未招募
1/2 期
Comparing Whole Body Vibration vs. Focal Vibration with Conventional Exercises on Older Adult BalanceCTRI/2024/06/068414MAEERs College of Physiotherapy Talegaon Dabhade40
尚未招募
不适用
Study on the Benefits of Whole-Body Vibration for Memory, Balance, and Function in Individuals with Knee Joint ProblemsCTRI/2025/05/086718SHARANIASELVI M N56
招募中
不适用
Precision Vibration Therapy for Neuromuscular and Functional Improvement in Older Adults and Stroke SurvivorsNCT07351877National Health Research Institutes, Taiwan80
尚未招募
1 期
To examine how vibration therapy helps older adults in improving balance and moving better: A Dosimetry studyCTRI/2024/01/061736Jamia Millia Islamia36
已完成
不适用
Two different therapies for treating nerve damage from chemotherapyCTRI/2024/07/071675Srushti Jegarkal38