A comparative study of fluid therapy with Ringer's and Ringer's lactate solution on acid and base status and blood electrolytes in patients with coronary artery bypass graft surgery

Phase 1

Recruiting

• Conditions: se of Ringer lactate serum.

• Registration Number: IRCT20161127031131N2
• Lead Sponsor: Rajaei Cardiovascular Medical and Research Center

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 29 November 2021

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 160

Inclusion Criteria

1. Age 30 to 70 years - 2.Weight 30 to 100 kg 3. No license for severe kidney or liver disease (creatinine more than 1.5 and liver enzymes more than 2 times normal) 4. Absence of severe heart failure (LVEF> 35%)

Exclusion Criteria

1. Cardiac arrest of the patient during surgery or on the first day in the intensive care unit, 2. Severe postoperative bleeding on the first day (more than 1000 ml) in the intensive care unit 3. The patient returns to the pump for any reason 4. Intra-aortic implantation of a balloon pump or ECMO for any reason 5.Transfer of the patient to the intensive care unit with an open sternum 6. Need for high-dose inotropes (epinephrine or norepinephrine greater than 0.2 micrograms per kilogram of body weight per minute)

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1.level of lactate. Timepoint: 1. When the patient enters the operating room 2. After induction of anesthesia 3. Time off from the pump 4.Upon entering the ICU 5.Until the hour after entering the ICU 6.12 hours after entering the ICU 7.18 hours after entering the ICU. Method of measurement: Arterial blood sample and blood gas analyzer.