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FreeStyle Libre Pro Use in Primary & Secondary Care

Not Applicable
Completed
Conditions
Diabetes Mellitus
Interventions
Device: FreeStyle Libre Pro 3 sensor wears
Device: FreeStyle Libre Pro 4 sensor wears, 2 with reviews
Device: FreeStyle Libre Pro 6 sensor wears, 4 with reviews
Registration Number
NCT02434315
Lead Sponsor
Abbott Diabetes Care
Brief Summary

The purpose of this study is to evaluate the impact of varying amount of FreeStyle Libre Pro wear as measured by time in range.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
175
Inclusion Criteria
  • Age at least 18 years.
  • Type 2 diabetes treated with insulin therapy for at least 6 months prior to study enrolment.
  • HbA1c between 58 and 108 mmol/mol (7.5 and 12.0%) inclusive.
Exclusion Criteria
  • Age at least 18 years.
  • Type 2 diabetes treated with insulin therapy for at least 6 months prior to study enrolment.
  • HbA1c between 58 and 108 mmol/mol (7.5 and 12.0%) inclusive.
  • Participant is currently prescribed animal insulin.
  • Total daily dose of insulin (TDD) is >1.75 iu/kg at entry to the study.
  • Concomitant disease or condition that may compromise patient safety including and not limited to; cystic fibrosis, severe mental illness, a diagnosed or suspected eating disorder or any uncontrolled long term medical condition.
  • Has a pacemaker or any other neurostimulators.
  • Currently prescribed oral, intramuscular or intravenous steroid therapy for any acute or chronic condition or requires it during the study period.
  • Currently receiving dialysis treatment or planning to receive dialysis during the study.
  • Women who are pregnant, plan to become pregnant or become pregnant during the study.
  • Participating in another study of a glucose monitoring device or drug that could affect glucose measurements or management.
  • Currently using / has previously used a sensor based Glucose Monitoring System (including retrospective glucose monitoring system) within the last 6 months.
  • Currently using Continuous Subcutaneous Insulin Infusion (CSII).
  • Known (or suspected) allergy to medical grade adhesives.
  • In the investigator's opinion the participant is unsuitable to participate due to any other cause/reason.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Group A - ControlFreeStyle Libre Pro 3 sensor wearsFreeStyle Libre Pro 3 sensor wears
Group B - InterventionFreeStyle Libre Pro 4 sensor wears, 2 with reviewsFreeStyle Libre Pro 4 sensor wears, 2 with reviews
Group C - InterventionFreeStyle Libre Pro 6 sensor wears, 4 with reviewsFreeStyle Libre Pro 6 sensor wears, 4 with reviews
Primary Outcome Measures
NameTimeMethod
Change from Baseline - time in glucose range - for penultimate sensor wear14 day baseline phase compared to day 172 to 187

Within arm difference in time in range in penultimate period of sensor wear compared to baseline phase

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (23)

Westongrove Partnership

🇬🇧

Aylesbury, United Kingdom

Omnia Practice

🇬🇧

Birmingham, United Kingdom

Atherstone Surgery

🇬🇧

Atherstone, United Kingdom

Pebsham Surgery

🇬🇧

Bexhill, United Kingdom

Hathaway Surgery

🇬🇧

Chippenham, United Kingdom

Rowden Surgery

🇬🇧

Chippenham, United Kingdom

Pound Hill Medical Group

🇬🇧

Crawley, United Kingdom

Claremont Medical Practice

🇬🇧

Exmouth, United Kingdom

White Horse Medical Practice

🇬🇧

Faringdon, United Kingdom

James Cook Hospital

🇬🇧

Middlesborough, United Kingdom

Kings College Hospital

🇬🇧

London, United Kingdom

Parkwood Surgery

🇬🇧

Hemel Hempstead, United Kingdom

St James Hospital,

🇬🇧

Leeds, United Kingdom

Milton Keynes Hospital

🇬🇧

Milton Keynes, United Kingdom

Greenwood and Sneinton Centre

🇬🇧

Nottingham, United Kingdom

Mortimer Surgery

🇬🇧

Reading, United Kingdom

Clifton Medical Centre

🇬🇧

Rotherham, United Kingdom

Ashfields Primary Care Centre

🇬🇧

Sandbach, United Kingdom

Salford Royal Hospital

🇬🇧

Salford, United Kingdom

The Kiltearn Medical Centre

🇬🇧

Sandbach, United Kingdom

Friarsgate Practice

🇬🇧

Winchester, United Kingdom

Albany House Surgery

🇬🇧

Wellingborough, United Kingdom

Rothwell Surgery

🇬🇧

Wellingborough, United Kingdom

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