The Effect of Low-Level Laser Therapy as an Adjunct to Non-surgical Therapy on Inducible Nitrous Oxide Synthase Salivary Levels in Different Age Groups of Chronic Periodontitis Patients (A Randomized Clinical Trial)
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 44
- 试验地点
- 3
- 主要终点
- clinical parameters (gingival index)
研究概览
简要总结
the summary is to evaluate The Effect of Low-Level Laser Therapy as an Adjunct to Non-surgical Therapy on Inducible Nitrous Oxide Synthase Salivary Levels in Different Age Groups of Chronic Periodontitis Patients
详细描述
2 ml of unstimulated saliva will be collected using spitting method, the collected samples will then be analyzed using Elisa technique for salivary Inducible nitrous oxide synthase levels.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Care Provider, Outcomes Assessor)
入排标准
- 年龄范围
- 60 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •males and females
- •aged below 40 or above 60
- •periodontitis stage 2
- •no tooth loss due to periodontitis
排除标准
- •smoking habits
- •history of antibiotics
- •history of systemic diseases
结局指标
主要结局
clinical parameters (gingival index)
时间窗: 6 months
measurement if the gingival index using scoring system. A score from 0.1-1.0 = mild inflammation; 1.1-2.0 = moderate inflammation from, and 2.1-3.0 signifies severe inflammation.
clinical parameters (clinical attachment loss)
时间窗: 6 months
measurement of clinical parameters clinical attachment loss in millimeters
次要结局
- assessment of inducible nitrous oxide synthase levels(3 months)
研究者
Alaa Allah Hesham
Bachelor's Degree (research assistant)
Faculty of Dental Medicine for Girls