Effect of Yogic Practices on Biochemical Markers of Work-related Selected Musculoskeletal Disorders among IT Professionals
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 134
- 试验地点
- 1
- 主要终点
- Change in biochemical markers including inflammatory markers IL1 IL6 and TNF alpha oxidative stress markers ROS MDA and SOD and neurotrophic factors NGF BDNF and Neurotrophin three from baseline to post intervention in information technology professionals with work related musculoskeletal disorders such as Carpal Tunnel Syndrome Cervical Radiculopathy and Lower Back Pain following yogic practices compared to a control group.
研究概览
简要总结
This randomized controlled trial aims to evaluate the effect of a structured yogic practice program on biochemical and clinical outcomes of selected work-related musculoskeletal disorders among information technology professionals. Eligible participants diagnosed with carpal tunnel syndrome, cervical radiculopathy, or lower back pain will be screened and randomly assigned to experimental and control groups. The experimental group will receive a 12 week yogic practice program while the control group will continue routine lifestyle practices without intervention. The primary outcomes include changes in biochemical markers such as inflammatory markers, oxidative stress markers, and neurotrophic factors. Secondary outcomes include improvements in clinical assessment tests, electromyography, reduced pain, improved musculoskeletal function, and enhanced occupational performance. The study aims to establish yoga as a cost effective safe and non invasive intervention for promoting health and productivity among information technology professionals with work related musculoskeletal disorders.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 30.00 Year(s) 至 45.00 Year(s)（—）
- 性别
- All
入选标准
- •Participants must be between 30 and 45 years of age.
- •Participants must be currently employed as an information technology professional with a minimum of two years of work experience in the industry.
- •Participants must have a clinically diagnosed work related musculoskeletal disorder such as Carpal Tunnel Syndrome Cervical Radiculopathy or Lower Back Pain confirmed through physical examination and appropriate diagnostic tests including Tinel sign Phalen test Spurling test and straight leg raise test.
- •Participants must work at least thirty five hours per week in a predominantly sedentary occupation involving prolonged computer use.
- •Participants must be willing to participate in a twelve week yogic intervention program and comply with the study protocol.
- •Participants must provide written informed consent prior to participation in the study.
排除标准
- •Individuals with severe or advanced musculoskeletal disorders requiring surgical intervention or those who have undergone musculoskeletal surgery within the past one year.
- •Participants with chronic medical conditions such as cardiovascular diseases or autoimmune disorders that may influence the study outcomes.
- •Individuals who have practiced yoga or similar physical activity programs such as Pilates or Tai Chi on a regular basis more than twice per week during the previous six months.
- •Pregnant women or women planning pregnancy during the study period.
- •Participants with severe psychiatric illness or cognitive impairment that may interfere with adherence to the study protocol.
- •Individuals who are currently participating in any other clinical trial or therapeutic intervention that could affect the study outcomes.
结局指标
主要结局
Change in biochemical markers including inflammatory markers IL1 IL6 and TNF alpha oxidative stress markers ROS MDA and SOD and neurotrophic factors NGF BDNF and Neurotrophin three from baseline to post intervention in information technology professionals with work related musculoskeletal disorders such as Carpal Tunnel Syndrome Cervical Radiculopathy and Lower Back Pain following yogic practices compared to a control group.
时间窗: Baseline | At twelve weeks post-intervention
次要结局
- Change in Tinel’s Sign, Phalen’s Test, Spurling’s Test, and Straight Leg Raise Test results(baseline (Week 0) and post-intervention (Week 12))
- Change in Electromyography (EMG)(baseline (Week 0) and post-intervention (Week 12))
- hange in functional disability assessed by disease-specific scales (DASH for Carpal Tunnel Syndrome, Neck Disability Index for Cervical Radiculopathy, Oswestry Disability Index for Low Back Pain)(baseline (Week 0) and post-intervention (Week 12))
研究者
Pedasingu Sharmila Devi
Central University of Kerala