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Clinical Trials/NCT05614193
NCT05614193
Recruiting
Not Applicable

Deep Enhanced Imaging in Stroke and Vascular Neurology

Chinese PLA General Hospital1 site in 1 country1,000 target enrollmentDecember 1, 2022

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Radiology
Sponsor
Chinese PLA General Hospital
Enrollment
1000
Locations
1
Primary Endpoint
The performance of deep enhanced imaging in lesion detection and diagnosis
Status
Recruiting
Last Updated
3 years ago

Overview

Brief Summary

To investigate the performance of enhanced computed tomography (CT) or magnetic resonance (MR) imaging by deep learning relative to conventional CT or MR imaging in brain stroke and vascular neurology. We expect that the deep enhanced imaging method can shorten the time stay in the imaging session of stroke patients, optimize the overall imaging quality and improve the patients' care in imaging session.

Detailed Description

Early diagnosis of cerebral infarction, detection of ischemic penumbra, evaluation of collateral circulation and identification of vascular lesions by imaging are critical for treatment decision and outcome improvement in cerebral stroke. Multimodal computed tomography (CT) and magnetic resonance (MR) imaging are most prevalent and accessible approaches in clinical scenarios. These two approaches are downgraded either by radiation exposure or long scanning time which may hinder the rapid treatment for patients. Deep learning has shown substantial achievements in medical imaging enhancement. The added value of deep learning method in stroke and vascular neurology has not been thoroughly validated. In this study, we aimed to investigate the performance of enhanced computed tomography (CT) or magnetic resonance (MR) imaging by deep learning relative to conventional CT or MR imaging in brain stroke and vascular neurology. We expect that the deep enhanced imaging method can shorten the time stay in the imaging session of stroke patients, optimize the overall imaging quality and improve the patients' care in imaging session.

Registry
clinicaltrials.gov
Start Date
December 1, 2022
End Date
December 31, 2027
Last Updated
3 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Chinese PLA General Hospital
Responsible Party
Principal Investigator
Principal Investigator

Xin Lou

Chairman

Chinese PLA General Hospital

Eligibility Criteria

Inclusion Criteria

  • suspecting to have experienced stroke or cerebral ischemia and needed to undergo brain imaging and vascular imaging including CT or MRI
  • no history of kidney failure
  • a minimum age of 18 years
  • obtained written informed consent

Exclusion Criteria

  • severe movement artifacts
  • incidental finding of tumor lesion or craniocerebral surgery history
  • poor imaging failed to perform deep learning method
  • women who pregnancy

Outcomes

Primary Outcomes

The performance of deep enhanced imaging in lesion detection and diagnosis

Time Frame: 1 year

The performance of deep enhanced imaging in lesion detection and diagnosis, including imaging quality, accuracy, sensitivity and specificity in lesion detection and imaging diagnosis.

Study Sites (1)

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