comparing surfactant administration techniques: LISA vs InSurE in preterm infants with RDS
Not Applicable
- Conditions
- Health Condition 1: P220- Respiratory distress syndrome of newborn
- Registration Number
- CTRI/2022/01/039147
- Lead Sponsor
- Government Medical College Aurangabad
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
spontaneously breathing preterm infants with RDS diagnosed within 24 h of life and meeting two or more criteria for surfactant therapy from 28 weeks 0 days to 36 weeks 6 daysâ?? gestational age.
Exclusion Criteria
infants with anatomical abnormalities of upper airway; major congenital anomalies; congenital diaphragmatic hernia; trachea-esophagealfistula; choanal atresia; cleft palate; and poor respiratory efforts. Also, infants requiring intubation and invasive ventilation due to hemodynamic instability or fraction of inspired oxygen (FiO2) requirement 0.6 were excluded.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method need of mechanical ventilation within 72 hours of birthTimepoint: need of mechanical ventilation within 72 hours of birth
- Secondary Outcome Measures
Name Time Method Incidence of major complications, length of hospital stay, duration of mechanical ventilation, duration of NIPPV, and survival outcomeTimepoint: till discharge or death