Maternal antiretroviral therapy in breast-fed HIV-exposed childre

Recruiting

• Conditions: Z20.6; Contact with and exposure to human immunodeficiency virus [HIV]

• Registration Number: DRKS00029318
• Lead Sponsor: Zentrum für Kinder- und Jugendmedizin, Uniklinik Freiburg

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2022-07-04
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

HIV exposed

Exclusion Criteria

HIV infection

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Are relevant quantities of the medicines transmitted through breast milk present in the breastfed children?<br>When? ongoing measurement during breastfeeding/follow-up after HIV exposure<br>What? drug levels.<br>How? routine blood collection

Secondary Outcome Measures

Name	Time	Method
Are there differences in laboratory parameters (e.g. cytopenia, elevated transaminases, hyperbilirubinemia) or clinical parameters (e.g. weight development, growth in height) between breastfed and non-breastfed HIV-exposed children?<br><br>When? continuous measurement during follow-up<br>What? Blood count, laboratory parameters<br>How? routine blood collection