Coconut Oil in Treatment of Periodontitis

Phase 1

Completed

• Conditions: Periodontal Diseases
• Interventions: Biological: topical application of coconut oil; Other: scaling and debridement

• Registration Number: NCT06384638
• Lead Sponsor: Misr University for Science and Technology

Brief Summary

Virgin Coconut Oil (VCO) is a vegetable oil extracted from coconut fleshcontains unsaturated fatty acids in the form of oleic acid and linoleic acid and flavonoids which function as anti-inflammatory. Periodontitis is an inflammatory disease of the periodontal tissues with a high prevalence worldwide. The main etiology of plaque periodontitis is biofilm containing colonies of pathogenic microorganisms. The aim of the study is to evaluate and compare the effect of scaling and root debridement alone versus the use of topically applied coconut oil as adjunctive to scaling and root debridement in treatment of Stage II and III Grade B periodontitis.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-02-15
• Primary Completion: 2024-01-16
• Study Completion: 2024-02-09
• Status Verified: 2024-04
• Study First Submitted: 2024-04-19
• Study First Submitted QC: 2024-04-24
• Last Update Submitted: 2024-04-24
• Study First Posted: 2024-04-25
• Last Update Posted: 2024-04-25

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 34

Inclusion Criteria

• patients age group >35 years without ant systemic disease
• Willing to take part in the study. Patients with more than 16 natural teeth and have test teeth with both mesial and distal neighboring teeth with periodontitis with clinical attachment loss >3 mm and radiographic percentage of bone loss/age ranged between 0.25 to 1.
• Patients with no history of allergies to coconut

Exclusion Criteria

• smokers
• pregnant
• lactating women
• Teeth with both endodontic-periodontal lesion.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
interventional	scaling and debridement	coconut oil as topical application as adjunctive to scaling and root debridement
interventional	topical application of coconut oil	coconut oil as topical application as adjunctive to scaling and root debridement
control	scaling and debridement	scaling and root debridement

Primary Outcome Measures

Name	Time	Method
clinical parameters	3 months	Probing depth

Secondary Outcome Measures

Name	Time	Method
Biological parameters	3 months	Tumor necrosis factor alpha (TNF- α) levels by using ELISA.

Trial Locations

Locations (1)

Faculty of dentistry at MUST; 🇪🇬 Giza, Egypt