Blood and blood products transfusion for major surgeries in children.
Not Applicable
- Conditions
- Health Condition 1: J982- Interstitial emphysemaHealth Condition 2: K831- Obstruction of bile ductHealth Condition 3: K689- Other disorders of retroperitoneumHealth Condition 4: C7A8- Other malignant neuroendocrine tumorsHealth Condition 5: K928- Other specified diseases of the digestive systemHealth Condition 6: K766- Portal hypertensionHealth Condition 7: B948- Sequelae of other specified infectious and parasitic diseases
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Children posted for all major surgeries under balanced anesthesia for which blood or/and blood products will be arranged. A minimum of 250 such children will be included.
Exclusion Criteria
1. Parental refusal to participate in study.
2. Surgeries under local/regional anesthesia.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To study the impact of peri-operative blood transfusion on 30-days mortality in children undergoing major surgical procedures.Timepoint: 30th day
- Secondary Outcome Measures
Name Time Method 1. To determine the transfusion-triggering hemoglobin threshold level in the study participants. <br/ ><br>2. To identify the impact of peri-operative blood transfusion and various factors (patient, anesthesia, surgical) on post-operative morbidity (defined as per ACS-NSQIP Convention, hypotension, thrombocytopenia, electrolyte abnormality, hypoglycemia, seizure, active bleed or anastomotic leak) and mortality.Timepoint: 1. Intraoperative (just before starting PRBC). <br/ ><br>2. upto 30 days.