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Clinical Trials/NCT07545824
NCT07545824
Not yet recruiting
Not Applicable

Association Between Ultrasound-Derived Rectus Abdominis Muscle Thickness and Thickening Fraction and Postoperative Opioid Consumption in Geriatric Patients Undergoing Abdominal Surgery: A Prospective Observational Study

Istinye University1 site in 1 country62 target enrollmentStarted: April 25, 2026Last updated:

Overview

Phase
Not Applicable
Status
Not yet recruiting
Sponsor
Istinye University
Enrollment
62
Locations
1
Primary Endpoint
Postoperative Total Opioid Consumption

Overview

Brief Summary

This prospective observational study aims to evaluate the relationship between ultrasound-derived rectus abdominis muscle thickness and thickening fraction and postoperative opioid consumption in geriatric patients undergoing abdominal surgery. Preoperative ultrasonographic measurements will be performed during routine clinical care, and postoperative pain scores and analgesic requirements will be recorded within the first 24 hours. The findings may help improve individualized analgesic strategies by identifying patient-specific predictors of postoperative opioid needs.

Study Design

Study Type
Observational
Observational Model
Cohort
Time Perspective
Prospective

Eligibility Criteria

Ages
65 Years to — (Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Age ≥65 years
  • Scheduled for elective midline abdominal surgery
  • ASA physical status I-III
  • Planned to receive bilateral ultrasound-guided rectus sheath block as part of routine clinical practice
  • Provided written informed consent

Exclusion Criteria

  • Known allergy or hypersensitivity to local anesthetics
  • Infection or skin lesion at the injection site
  • Systemic infection or sepsis
  • Coagulopathy (INR \>1.5 or platelet count \<100,000/mm³)
  • Use of therapeutic anticoagulation not safely managed perioperatively
  • History of previous midline laparotomy
  • History of abdominal mesh implantation or abdominal wall reconstruction
  • Significant abdominal wall pathology (e.g., large hernia) affecting anatomy
  • Neuromuscular disease (e.g., myasthenia gravis, ALS, muscular dystrophy)
  • Inability to perform required maneuver for dynamic ultrasound measurement

Outcomes

Primary Outcomes

Postoperative Total Opioid Consumption

Time Frame: First 24 hours postoperatively

Total opioid consumption within the first 24 hours after surgery will be recorded and converted to morphine equivalents (mg). This measure will be used to evaluate the association between ultrasound-derived rectus abdominis muscle parameters and postoperative analgesic requirements.

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor
Istinye University
Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

İlke Dolgun

assoc.prof

Istinye University

Study Sites (1)

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