Association Between Ultrasound-Derived Rectus Abdominis Muscle Thickness and Thickening Fraction and Postoperative Opioid Consumption in Geriatric Patients Undergoing Abdominal Surgery: A Prospective Observational Study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 62
- 试验地点
- 1
- 主要终点
- Postoperative Total Opioid Consumption
研究概览
简要总结
This prospective observational study aims to evaluate the relationship between ultrasound-derived rectus abdominis muscle thickness and thickening fraction and postoperative opioid consumption in geriatric patients undergoing abdominal surgery. Preoperative ultrasonographic measurements will be performed during routine clinical care, and postoperative pain scores and analgesic requirements will be recorded within the first 24 hours. The findings may help improve individualized analgesic strategies by identifying patient-specific predictors of postoperative opioid needs.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 65 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age ≥65 years
- •Scheduled for elective midline abdominal surgery
- •ASA physical status I-III
- •Planned to receive bilateral ultrasound-guided rectus sheath block as part of routine clinical practice
- •Provided written informed consent
排除标准
- •Known allergy or hypersensitivity to local anesthetics
- •Infection or skin lesion at the injection site
- •Systemic infection or sepsis
- •Coagulopathy (INR >1.5 or platelet count <100,000/mm³)
- •Use of therapeutic anticoagulation not safely managed perioperatively
- •History of previous midline laparotomy
- •History of abdominal mesh implantation or abdominal wall reconstruction
- •Significant abdominal wall pathology (e.g., large hernia) affecting anatomy
- •Neuromuscular disease (e.g., myasthenia gravis, ALS, muscular dystrophy)
- •Inability to perform required maneuver for dynamic ultrasound measurement
- •Moderate to severe cognitive impairment or poor cooperation
- •Body mass index (BMI) >40 kg/m²
- •Cachexia or severe malnutrition
- •Chronic opioid use (≥3 months)
- •Chronic pain syndromes requiring regular analgesic use
- •Alcohol or substance abuse
- •Emergency surgery
- •Use of additional regional anesthesia techniques (e.g., epidural, TAP block)
- •Inadequate ultrasound visualization of the target anatomical plane
结局指标
主要结局
Postoperative Total Opioid Consumption
时间窗: First 24 hours postoperatively
Total opioid consumption within the first 24 hours after surgery will be recorded and converted to morphine equivalents (mg). This measure will be used to evaluate the association between ultrasound-derived rectus abdominis muscle parameters and postoperative analgesic requirements.
次要结局
未报告次要终点
研究者
İlke Dolgun
assoc.prof
Istinye University