Efficacy of Pre-extubation High Dose vs Low Dose Caffeine Administration For Success of Weaning in Mechanically Ventilated Newborns - A Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 128
- 试验地点
- 1
- 主要终点
- To compare pre-extubation high and low dose caffeine administration in mechanically
研究概览
简要总结
Primary Objective - To compare pre-extubation high and low dose caffeine administration in mechanically
ventilated newborns for success of weaning in terms of :
-
Re-intubation rates
-
Duration of non-invasive ventilation needed
研究设计
- 研究类型
- Interventional
- 分配方式
- Other
入排标准
- 年龄范围
- 1.00 Day(s) 至 3.00 Month(s)（—）
- 性别
- All
入选标准
- •All newborns admitted in the Neonatal intensive care unit.
- •All newborns with invasive mechanical ventilation of more than 48 hours.
排除标准
- •All healthy newborns in the Postnatal care unit are excluded.
- •All newborns with invasive mechanical ventilation of less than 48 hours.
结局指标
主要结局
To compare pre-extubation high and low dose caffeine administration in mechanically
时间窗: Newborns will be assessed daily i.e every 24 hourly till they are weaned completely off non invasive ventilation
ventilated newborns for success of weaning in terms of :
时间窗: Newborns will be assessed daily i.e every 24 hourly till they are weaned completely off non invasive ventilation
1. Re-intubation rates
时间窗: Newborns will be assessed daily i.e every 24 hourly till they are weaned completely off non invasive ventilation
2. Duration of non-invasive ventilation needed
时间窗: Newborns will be assessed daily i.e every 24 hourly till they are weaned completely off non invasive ventilation
次要结局
- To compare the efficacy of high-dose & low-dose caffeine administration in reducing the(duration of supplemental oxygen requirement post-extubation in mechanically ventilated)
研究者
Yusuf Khairullah
N. K. P. Salve Institute Of Medical Sciences and Research Centre And Lata Mangeshkar Hospital