Comparison between high dose and low dose laser therapy (Nd:YAG laser) for facial pigmentation (melasma)

Completed

Conditions: All patients of refractory melasma who have not shown complete clearance after 6 weeks of topical triple combination therapy and topical sunscreens attending the dermatology OPD

Registration Number: CTRI/2018/07/014864

Lead Sponsor: Department of Dermatology JIPMER

Brief Summary: In this trial, we aim to compare between laser treatment regimens involving low fluence and high fluence Q-switched Nd:YAG laser for melasma refractory to topical medications. This study aims to identify the ideal treatment regimen in dark skinned individuals of our population so as to maximize clinical efficacy and minimise side effects

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: All

Target Recruitment: 40

Inclusion Criteria

All patients of refractory melasma who have not shown complete clearance after 6 weeks of topical triple combination therapy and topical sunscreens attending the dermatology OPD.

Exclusion Criteria

Other causes of facial melanosis (such as lichen planus pigmentosus, erythema dyschronicum perstans, pigmented contact dermatitis, post-inflammatory hyperpigmentation) 2.
Pregnant and lactating mothers 3.
Patients currently using oral contraceptives 4.
History of endocrinopathies.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Post-treatment Melasma Area and Severity Index (MASI) scores	3 months

Secondary Outcome Measures

Name	Time	Method
Side effects	3 months

Trial Locations

Locations (1): JIPMER
🇮🇳
Pondicherry, PONDICHERRY, India
JIPMER
🇮🇳Pondicherry, PONDICHERRY, India
Dr Jude Ernest Dileep
Principal investigator
9159930448
judegenext@gmail.com