Effect of Passive Smoking on Oxidative Stress and Dental Caries in Children
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 180
- 主要终点
- determining caries prevalence
研究概览
简要总结
The purpose of the present study was to determine the effect of passive smoking on oxidative stress and dental caries in children.A total of 180 children were included to the study as follows; 90 children exposed to passive smoking, and 90 children in the control group (unexposed controls). Also demographic data were recorded (age, gender, parental education levels, child's tooth-brushing habit and child's daily dietary sugar exposure, family income). Dental examination of children were performed and caries prevalence of the patients were recorded. Unstimulated saliva samples were collected from children. Saliva 'cotinine levels' and oxidative stress markers 'total antioxidant status' (TAS), and' total oxidant status' (TOS) were evaluated by using Enzyme-linked immunosorbent assay (ELISA). The obtained data parameters of the two groups were evaluated and comparison was performed.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 6 Years 至 12 Years（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Systemically healthy children
排除标准
- •Uncooperative children
- •The presence of orthodontic/intraoral appliance
- •Any disease or condition known to affect oxidative stress
结局指标
主要结局
determining caries prevalence
时间窗: 1 day (once for dental examination)
Children were examined to determine caries prevalence.
determining oxidative stress marker in saliva: TOS
时间窗: 1 day (once after the dental examination)
Unstimulated saliva samples were collected from children.
determining oxidative stress marker in saliva: TAS
时间窗: 1 day (once after the dental examination)]
Unstimulated saliva samples were collected from children.
次要结局
未报告次要终点
研究者
Merve Erkmen Almaz
Assist prof
Kırıkkale University