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Clinical Trials/ISRCTN51917813
ISRCTN51917813
Completed
Not Applicable

An investigation into the effects of cessation of clopidogrel therapy on vascular inflammation and platelet reactivity in patients with drug-eluting coronary stents: is there a rebound phenomenon?

Southampton University Hospitals NHS Trust (UK)0 sites60 target enrollmentApril 23, 2010
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ConditionsTopic: CardiovascularSubtopic: Cardiovascular (all Subtopics)Disease: CardiovascularCirculatory SystemPercutaneous coronary intervention

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Topic: Cardiovascular
Sponsor
Southampton University Hospitals NHS Trust (UK)
Enrollment
60
Status
Completed
Last Updated
11 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
April 23, 2010
End Date
TBD
Last Updated
11 years ago
Study Type
Interventional
Sex
All

Investigators

Sponsor
Southampton University Hospitals NHS Trust (UK)

Eligibility Criteria

Inclusion Criteria

  • •1\. Aged greater than 18 years, either sex
  • •2\. Signed written informed consent
  • •3\. Prior percutaneous coronary intervention (PCI) with drugeluting stent implantation and due to stop clopidogrel 12 months after PCI
  • •4\. On maintenance dose aspirin 75 mg and clopidogrel 75 mg daily
  • •5\. 30 diabetics and 30 nondiabetics

Exclusion Criteria

  • •1\. Aged greater than 85 years
  • •2\. On regular nonsteroidal antiinflammatory medication or steroids

Outcomes

Primary Outcomes

Not specified

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