Evaluation of Plasmatic Magnesium Levels and Its Association with Atrial Fibrillation After Cardiac Surgery
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 435
- 试验地点
- 1
- 主要终点
- Postoperative Atrial fibrilation
研究概览
简要总结
Introduction: Postoperative atrial fibrillation is one of the most frequent complications in cardiac surgery, with an expected incidence of more than 50% following valve surgery. Hypomagnesemia is also likely to be observed in the postoperative period, and several studies have suggested that it could be related to the incidence of postoperative atrial fibrillation. In this study, via a prospective design and adjustment for multiple covariates, the investigators will seek to determine whether plasma magnesium levels are independently associated with the appearance of postoperative atrial fibrillation.
Methods: An analytical design involving a concurrent cohort will be carried out in a high-complexity hospital with a cardiovascular focus. Serial postoperative plasma magnesium measurements will be included as independent variables in a logistic regression model to determine their association with atrial fibrillation after adjusting for multiple covariates.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adults in postoperative cardiac surgery
排除标准
- •Preoperative atrial fibrillation
- •Without complete information regarding plasmatic magnesium postoperative measurements
结局指标
主要结局
Postoperative Atrial fibrilation
时间窗: Measurement was performed first day after surgery up to 30 days postoperatively or discharge (whichever came first)
Defined as irregular QRS without p wave during 30 seconds in a 12 derivations EKG.
次要结局
- Mortality(Measurement was performed first day after surgery up to 30 days postoperatively or discharge (whichever came first))
研究者
Edgar Hernández Leiva
Head of Cardiovascular Critical Care
Fundación Cardioinfantil Instituto de Cardiología
