jRCT1050230199RecruitingNot Applicable
Retinal image analysis using ultra-high resolution fundus imaging devices utelizing adaptive optics
Kobe City Hospital Organization Kobe City Eye Hospital0 sites220 target enrollmentStarted: February 15, 2024Last updated:
Trial Snapshot
- Phase
- Not Applicable
- Status
- Recruiting
- Sponsor
- Enrollment
- 220
- Primary Endpoint
- Morphological observation and quantitative evaluation of photoreceptor cells
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Observational
Eligibility Criteria
- Ages
- 20age old over to No limit (—)
Inclusion Criteria
- •(1) patients with retinochoroidal diseases, (2) patients with retinitis pigmentosa, (3) patients with glaucoma,
- •(4) patients with uveitis, (5) patients scheduled for transplantation of iPS cell-derived retinal cells, (6) patients after iPS cell-derived retinal cell transplantation. In addition, (7) healthy volunteers will be used to photograph normal eyes.
- •Selection criteria
- •(1) Persons 20 years of age or older.
- •(2) Persons who have consented to participate in this research.
Exclusion Criteria
- •(1) Persons judged by the principal researcher to be inappropriate as research subjects
- •(2) The following persons fall under the contraindications and prohibitions of using the AO fundus imaging device:
- •Those with a history of photosensitivity; those who have recently received photodynamic therapy (PDT) (Please refer to the package insert of the photosensitive substance administered for the prohibited period);those who are taking medicines that may cause photosensitivity
Outcomes
Primary Outcomes
Morphological observation and quantitative evaluation of photoreceptor cells
Morphological observation and quantitative evaluation of photoreceptor cells (cell density, etc.) using m2OCT
Morphological observation and quantitative evaluation of retinal pigment epithelial cells
Morphological observation and quantitative evaluation of retinal pigment epithelial cells using TFI-rtx1 (cell density, etc.)
Comparison of captured images of rtx1 and TFI-rtx1
Comparison of captured images of rtx1 and TFI-rtx1
Secondary Outcomes
No secondary outcomes reported
Investigators
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