Study of the effect of N-acetyl cysteine on biomarker of delayed graft function in cadaveric renal transplant recipients
Not Applicable
- Conditions
- Kidney transplant.Kidney transplant status
- Registration Number
- IRCT2014090214693N4
- Lead Sponsor
- Shahid Beheshti Medical University, School of Pharmacy and Shahid Labbafinejad Medical Center and Ur
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 70
Inclusion Criteria
inclusion criteria: kidney transplant recepients from deceased-donor; over 18 years of age
exclusion criteria: Recent stroke; hyperoxaluria; Sensitivity to sulfonamides; PRA>30%; Second transplantation; Less then 2 cc urine volume before transplantation
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method rine and plasma NGAL. Timepoint: pre-transplantation, dar 1 and 5 after transplantation. Method of measurement: ELISA kit.
- Secondary Outcome Measures
Name Time Method eed for dialysis in the firs week post transplantation or creatinine reduction ratio less than 10% per day in 3 consecutive days after transplantation. Timepoint: daily. Method of measurement: laboratory reports for SrCr and clinical sign and symptoms for dialysis.