Identifying Molecular Drivers of Cancer
- Conditions
- CancerTumorAdvanced Cancer
- Interventions
- Genetic: Molecular profile
- Registration Number
- NCT02470715
- Lead Sponsor
- Avera McKennan Hospital & University Health Center
- Brief Summary
The primary aim of this study is to identify drivers of cancer by performing comprehensive genetic, proteomic, and metabolomic characterization of patient samples as a basis for understanding the underlying cause of disease.
- Detailed Description
This study involves looking at the DNA, RNA, proteins, and metabolites in blood and tissue samples collected from subjects and linking them to their health information. By doing so, researchers hope to discover the underlying molecular causes of human diseases with the hope that this information can be used for the development of diagnostic tests and more effective treatments.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 579
- Patients diagnoses with cancer but healthy enough to undergo a biopsy procedure
- Between the ages of 18 and 100
- Patients who are pregnant
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Molecular profile Molecular profile Molecular profiled group receiving treatment based on genetics
- Primary Outcome Measures
Name Time Method Genetic profiling Up to 15 years To determine genetic changes associated with the development and growth of human disease. This should lead to better ways to detect, prevent, and treat a wide variety of human health conditions, including cancer.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Avera Cancer Institute
🇺🇸Sioux Falls, South Dakota, United States