Effect Of Two Doses Of Magnesium Sulfate On Hemodynamic Stability During Induction And Orotracheal Intubation In Adult Diabetic Patients

Phase 2

Completed

• Conditions: Diabetes; Anaesthesiology - Anaesthetics; Hemodynamic Stability During Induction And Orotracheal Intubation; Metabolic and Endocrine - Diabetes

• Registration Number: ACTRN12614001012662
• Lead Sponsor: dr doaa rashwan

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2014-09-19
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

50 ASA II males and females patients aged 40-65 years old, with controlled type II diabetes mellitus planned for elective surgery under general anesthesia requiring orotracheal intubation.

Exclusion Criteria

Patients will be excluded from the study if they had history of
type I diabetes mellitus, hypertension, cardiac disease, hypomagnesemia or hypermagenesmia , a known allergy to the study drugs, neuromuscular, liver and renal diseases ,suspected or history of difficult intubation, prolonged intubation longer than 30 secs or more than one attempt required, BMI >30 .
Patients undergoing cardiac and neurosurgical procedures will be also excluded.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The systolic arterial blood pressure<br>noninvasive monotoring[will be measured and recorded:<br> a- Before the administration of the study drug at baseline <br>b-after induction of anesthesia<br> c –at 1,5,10 minutes following tracheal intubation and before skin incision. <br>]; diastolic arterial blood pressure <br>noninvasive monotoring[ will be measured and recorded:<br> a- Before the administration of the study drug at baseline <br>b-after induction of anesthesia<br> c –at 1,5,10 minutes following tracheal intubation and before skin incision. <br>]; mean arterial blood pressure <br>noninvasive monotoring[will be measured and recorded:<br> a- Before the administration of the study drug at baseline <br>b-after induction of anesthesia<br> c –at 1,5,10 minutes following tracheal intubation and before skin incision. <br>]

Secondary Outcome Measures

Name	Time	Method
heart rate<br>ECG [ will be measured and recorded:<br> a- Before the administration of the study drug at baseline <br>b-after induction of anesthesia<br> c –at 1,5,10 minutes following tracheal intubation and before skin incision. <br>]