The Effect of Chloroquine in the Treatment of Patients With Dengue

Phase 1

• Conditions: Dengue
• Interventions: Drug: Placebo; Drug: Chloroquine

• Registration Number: NCT00849602
• Lead Sponsor: University of Sao Paulo

Brief Summary

The objective of this study was to evaluate the effect of chloroquine in the treatment of patients with dengue.

Detailed Description

Not available

Study Timeline

• Study Start: 2008-02
• Primary Completion: 2008-05
• Status Verified: 2009-02
• Study First Submitted: 2009-02-23
• Study First Submitted QC: 2009-02-23
• Last Update Submitted: 2009-02-23
• Study First Posted: 2009-02-24
• Last Update Posted: 2009-02-24
• Study Completion: 2009-06

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 132

Inclusion Criteria

• Patients suspected of having dengue disease

• Patients were included in the study if they presented with fever and at least two other symptoms, such as:

  • headache
  • pain behind the eyes
  • muscle and bone or joint pains
  • nausea
  • vomiting
  • rash associated to dengue for less than 72 hours

Exclusion Criteria

• Pregnant
• Younger than 18-years old
• Either cardiac or neurologic disease

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
1	Placebo	-
2	Chloroquine	-

Primary Outcome Measures

Name	Time	Method
Duration of the disease	one week

Secondary Outcome Measures

Name	Time	Method
Intensity and days of fever and symptoms	one week

Trial Locations

Locations (1)

São Paulo University Medical School at Ribeirão Preto; 🇧🇷 Ribeirão Preto, SP, Brazil