Uterus Transplantation From Live Donor
Not Applicable
Completed
- Conditions
- Primary Uterine Infertility
- Interventions
- Procedure: uterine transplantation
- Registration Number
- NCT01844362
- Lead Sponsor
- Sahlgrenska University Hospital, Sweden
- Brief Summary
Uterus transplantation, as a possible future treatment for uterine factor infertility, has been developed in animal species during the last decade.
The study protocol includes transplantation of the uterus from a live donor (mother, relative, friend) into women with absolute uterine factor infertility (lack of uterus from birth or due to life saving hysterectomy).The recipient will be treated by standard immunosuppression and transfer of embryos (acquired by IVF before surgery) will be attempted when at least 12 months have passed from transplantation. Approval for a case series including up to 10 patients has been acquired.
- Detailed Description
The study is ongoing, with inclusion of 9 patients.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 9
Inclusion Criteria
- less than 39 years
- good general health
Exclusion Criteria
- poor ovarian resaerve or older than 39 years
- systemic or psychiatric disease
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Uterine transplantation uterine transplantation Patients undergo transplantation of the uterus from live donor.
- Primary Outcome Measures
Name Time Method surviving transplants (12 months) up to 3 years after transplantation
- Secondary Outcome Measures
Name Time Method pregnancy rate up to 3 years after transplantation
Trial Locations
- Locations (1)
Mats Brännström
🇸🇪Göteborg, Sweden