Influence of Intra Canal Medications on Postoperative Flare-up in Endodontic Re-treatment Cases

Not Applicable

• Conditions: Postoperative Pain; Pain, Dental
• Interventions: Combination Product: calcium hydroxide chlorhexidine combination; Other: calcium hydroxide intra-canal medicament

• Registration Number: NCT03064191
• Lead Sponsor: rayan rabie dahab

Brief Summary

Is to evaluate the influence of the calcium hydroxide / chlorhexidine combination and calcium hydroxide alone as an intra-canal medication in postoperative flare-up in two visits endodontic retreatment cases

Detailed Description

Problem: patient needs retreatment Intervention: calcium hydroxide chlorhexidine combination as an intra-canal medicament Control: calcium hydroxide alone as an intra-canal medicament Outcome: postoperative flare-up (pain and swelling) Time: after 7 days from 1st visit. population will be examined:

1. Patients' needs retreatment.

2. Patients in good health with no systemic disease (American Society of Anesthesiologists Class II)

3. Age range is between 20 and 50 years.

4. Patients who can understand the categorical tool (points)for measurement

5. Patients able to sign informed consent.

Study Timeline

• Study First Submitted: 2017-02-16
• Study First Submitted QC: 2017-02-21
• Study First Posted: 2017-02-24
• Status Verified: 2017-09
• Study Start: 2017-09
• Last Update Submitted: 2017-09-09
• Last Update Posted: 2017-09-12
• Primary Completion: 2018-03-13
• Study Completion: 2018-04-13

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 24

Inclusion Criteria

• 1. Patients' needs retreatment.
• 2. Patients in good health with no systemic disease (American Society of Anesthesiologists Class II)
• 3. Age range is between 20 and 50 years.
• 4. Patients who can understand the categorical tool (points)for measurement
• 5. Patients able to sign informed consent.

Exclusion Criteria

• 1. Complicating systemic disease
• 2. Having severe pain and/or acute apical abscesses
• 3. Being under 18 years of age
• 4. Using antibiotics or corticosteroids,
• 5. having multiple teeth that required retreatment to eliminate the possibility of pain referral
• 6. Having root canals that could not be treated well with initial root canal treatment.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
calcium hydroxide chlorhexidine	calcium hydroxide chlorhexidine combination	intervention: calcium hydroxide chlorhexidine combination an intra-canal medication composed of calcium hydroxide powder and chlorhexidine solution as a combination to be administered as intra-canal paste for decreasing postoperative symptoms
calcium hydroxide	calcium hydroxide intra-canal medicament	intervention: calcium hydroxide an intra-canal medicament composed of calcium hydroxide paste for decreasing postoperative symptoms and signs .

Primary Outcome Measures

Name	Time	Method
measuring patients postoperative pain and swelling following endodontic re-treatment sessions using Categorical (4 points) unit using questionnaire.	7 days between the 2 visits ( one week)	postoperative pain and swelling will be measured by:Categorical (4 points). The incidence of postoperative discomfort was recorded and expressed as numbers and percentages; Subjectively into 4 points: 1. no pain; 2. Mild pain: recognizable but not discomforting pain that required no analgesics.; 3. Moderate pain: discomforting but bearable pain(analgesics if used were effective in relieving pain); 4. Severe pain: difficult to bear (analgesics were effective in relieving pain). Patients with severe postoperative pain and/or occurrence of swelling were classified as flare-ups.3 Objectively : percussion test

Trial Locations

Locations (1)

Univeristy of Cairo; 🇪🇬 Cairo, Egypt