Study to to evaluate the occurrence of Myeloproliferative neoplasm (a type of disease in which the bone marrow makes too many RBC, platelets, or certain WBC) & to characterize treatment patterns & burden/ symptoms of illness under routine medical practice

Not Applicable

Completed

Recruitment & Eligibility

Inclusion Criteria

1. Male or female patients >= 18 years of age who have been diagnosed with a Ph-MPN

according to the 2008 revised World Health Organization criteria

2.Willing and able to provide written informed consent according to local guidelines prior to

any study procedures

3. Have availability of historical medical records that verify diagnosis

4. Willing to complete and literate in the language of the available health related quality of

life (HRQoL) instrument either alone or with minimal assistance from caregivers and/or

trained site personnel

Exclusion Criteria

1. According to the investigatorâ??s opinion, the patient is an unlikely candidate to obtain longterm

follow-up information for any reasons such as unavailability or severe concomitant

illnesses

2. Patients with active alcohol or drug addiction that would interfere with their ability to

comply with the study requirements

3. Patients with any concurrent condition that, in the Investigatorâ??s opinion, would

jeopardize the safety of the patient or compliance with the protocol

Primary Outcome Measures

Name	Time	Method
To describe the current diagnosis, treatment, pattern <br/ ><br>in ET, PV, and MF patients in routine clinical practiceTimepoint: Diagnosis, Treatment patterns (incidence, prevalence, <br/ ><br>drug therapy used, duration, reason for <br/ ><br>discontinuation, treatment dose adjustment) <br/ ><br>Sequencing/changes in therapies <br/ ><br>Reason/s to change treatment (including dose <br/ ><br>changes) <br/ ><br>Time to disease progression from baseline

Secondary Outcome Measures

Name	Time	Method
To assess the economic burden captured by medical <br/ ><br>resource utilizations using common reference units <br/ ><br>(e.g., number of hospital admissions and days in <br/ ><br>hospital)Timepoint: Change in frequency of resource utilization from <br/ ><br>baseline <br/ ><br>Change in frequency of resource utilization from <br/ ><br>current line of therapy to subsequent line of therapy;To describe patient QOL and the association of QOL <br/ ><br>with change of therapyTimepoint: QOL <br/ ><br>Change in QOL from baseline to change in therapy <br/ ><br>Change in QOL from current line of therapy to <br/ ><br>subsequent line of therapy