Effects of Intrapulmonary Percussive Ventilator on Respiratory Function

Not Applicable

Not yet recruiting

• Conditions: Airway Clearance Impairment
• Interventions: Device: Intrapulmonary Percussive ventilator

• Registration Number: NCT06000618
• Lead Sponsor: Shanghai 10th People's Hospital

Brief Summary

The goal of this clinical trial is to prove the benefit of intrapulmonary percussive ventilator in healthy volunteers. The main questions are:

* How can intrapulmonary percussive improve lung function？

* What is the subjective feeling through intrapulmonary percussive?

Participants will be undergoing treatment of intrapulmonary percussive. Then they will be assessed for lung function and EIT before and after intrapulmonary percussive.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2023-07-20
• Status Verified: 2023-08
• Study First Submitted QC: 2023-08-16
• Last Update Submitted: 2023-08-16
• Study First Posted: 2023-08-21
• Last Update Posted: 2023-08-21
• Study Start: 2023-09-01
• Primary Completion: 2023-12-30
• Study Completion: 2024-05-31

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: Male
• Target Recruitment: 20

Inclusion Criteria

• No respiratory system, heart disease
• Well cooperate with the MateNeb

Exclusion Criteria

• No respiratory illness such as influenza, pneumonia, asthma, bronchitis within the last month
• Couldn't finish three times pulmonary function test

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
experimental group	Intrapulmonary Percussive ventilator	The experimental group will undergo intrapulmonary percussive therapy

Primary Outcome Measures

Name	Time	Method
Pulmonary function test	through study completion, an average one hour	This test can assess the volunteer's lung ventilation and diffusion function.For example the max vital capacity (VCMAX),Forced vital capacity(FVC),Forced expiratory volume in one second(FEV1),functional residual capacity(FRC-SB),diffusion capacity of lung for carbon monoxide(DLCO) and so on.
Electrical Impedance Tomography of Pulmonary(EIT)	through study completion, an average one hour	EIT is a relatively advanced non-invasive monitoring technique for the lung function. This technology uses a strap attached to the chest to monitor electrical at 16 locations. The Ventilation in each area resistance of the lung is quantified according to the electrical resistance

Secondary Outcome Measures

Name	Time	Method
The safety and comfort	The treatment was scored once after the participants completed both low and high frequency intrapulmonary percussive.Up to one week.	Whether the technique has adverse reactions. How do the volunteers feel? We used a scale of 1 to 4 to show how the volunteers felt. 1 is the worst feeling. The volunteers were no longer willing to undergo the treatment. 4 means the volunteers felt better and breathed easier after the treatment. Be willing to undergo endoairway shock therapy again.

Trial Locations

Locations (1)

Shanghai Tenth People's Hospital; 🇨🇳 Shanghai, China