Investigation of continence, sexual- and bowel function after radical surgery for bladder cancer

Not Applicable

• Conditions: Bladder cancer treated with radical cystectomy; Cancer; Bladder cancer

• Registration Number: ISRCTN42949068
• Lead Sponsor: und University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-10-07
• Last Update Posted: 22 January 2024
• Study Completion: 2026-01-01

Recruitment & Eligibility

• Status: Ongoing
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

1. Aged 18 years or over
2. Planned radical cystectomy for bladder cancer

Exclusion Criteria

Previous pelvic radiation

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. Decline in sexual function measured using IIEF-5 questionnaire (erectile dysfunction) for male participants and FSFI (female sexual dysfunction) questionnaire for female participants before surgery (baseline) and 12 months post-operatively<br>2. Inontinence measured using the St Mark’s questionnaire (faecal incontinence) before surgery (baseline) and 12 months post-operatively<br>3. Rectal function is measured by manuvolumetry is measured by maximum closure pressure (MACP) and resting anal sphincter pressure (RASP) before surgery (baseline) and 12 months post-operatively

Secondary Outcome Measures

Name	Time	Method
Rectal function assessed preoperatively and postoperatively after radical cystectomy using transrectal manuvolumetry and transrectal ultrasound, before surgery (baseline) and 12 months post-operatively.