ROCkeTS: Refining Ovarian Cancer Test Accuracy Scores

Not Applicable

• Conditions: Topic: Cancer; Subtopic: Gynaecological Cancer; Disease: Ovary/Fallopian tube; Cancer

• Registration Number: ISRCTN17160843
• Lead Sponsor: niversity of Birmingham

Brief Summary

2016 Protocol article in https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4985790 protocol

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-06-03
• Last Update Posted: 3 April 2023
• Study Completion: 2023-10-31

Recruitment & Eligibility

• Status: Ongoing
• Sex: All
• Target Recruitment: 2450

Inclusion Criteria

1. Pre and postmenopausal women with symptoms of suspected OC
and either:
2. Raised Ca125
3. Abnormal USG

Exclusion Criteria

1. USG reveals non ovarian pathology, e.g. fibroids or simple ovarian cysts < 5cm in size (very low risk of malignancy)
2. Patients with normal pelvis USG
3. Patients who decline transvaginal scan
4. Patients unable to provide informed consent

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Sensitivity of the new algorithm

Secondary Outcome Measures

Name	Time	Method
Specificity of the new algorithm