A Comparison Of Nebulisation With Dexmedetomidine And Nebulisation With 4% Lignocaine Plus Dexmedetomidine For Awake Fibreoptic Intubation

Phase 2/3

Not yet recruiting

• Conditions: Medical and Surgical,

• Registration Number: CTRI/2021/10/037256
• Lead Sponsor: Indira Gandhi institute of medical sciences

Brief Summary

A COMPARATIVE EVALUATION OF EFFICACY OF NEBULIZATION WITH DEXMEDETOMIDINE AND NEBULIZATION WITH 4% LIGNOCAINE PLUS DEXMEDETOMIDINE FOR AWAKE FIBEROPTIC INTUBATION IN DIFFICULT AIRWAY SCENARIO

Different topical and regional techniques have been developed to subdue reflexes and facilitate awake fiberoptic intubation .It is essential to sufficiently anesthetize the upper airway and suppress the gag, swallow ,and cough reflexes prior to awake fiberoptic intubation and thus ensure patient comfort

PRIMARY OBJECTIVES:

A comparative double blinded randomised study will be performed-

1) To evaluate the effect of preoperative nebulisation with dexmedetomidine and preoperative nebulisation with dexmedetomidine plus lignocaine for awake fiberoptic intubation on-

a) sedation/alertness

b) vocal cord /limb movement

c) coughing

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2021-09-29
• Study Start: 2021-10-17

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

patient consent, ASA grade 1 and 2, patient with anticipated difficult intubation(LEMON >2), BMI >30 kg/m2.

Exclusion Criteria

patient refusal, airway hypersensitivity, allergy to drugs used (lignocaine/dexmedetomidine),epileptic patients,patients with poor cardiopulmonary reserve, bleeding tendency, obesity, other co-morbid conditions.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1.sedation/alertness(OAA SCORE)	0 to 5 min
2.vocal cord movement(%)	0 to 5 min
3.limb movement	0 to 5 min
4.fibreoptic intubation score	0 to 5 min
5.coughing	0 to 5 min

Secondary Outcome Measures

Name	Time	Method
1) To compare the hemodynamic changes of two groups	2) Dose sparing effect of propofol

Trial Locations

Locations (1)

INDIRA GANDHI INSTITUTE OF MEDICAL SCIENCES,PATNA; 🇮🇳 Patna, BIHAR, India

INDIRA GANDHI INSTITUTE OF MEDICAL SCIENCES,PATNA

🇮🇳Patna, BIHAR, India

Dr Arvind Kumar

Principal investigator

8789655581

arvind007kumar@yahoo.com