Creation, Evaluation and Validation of a Preoperative Frailty Index Using Health Administrative Data: a Population-based Cohort Study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Frail Elderly Syndrome
- Sponsor
- Ottawa Hospital Research Institute
- Enrollment
- 200000
- Primary Endpoint
- Survival for One Year After Surgery
- Status
- Completed
- Last Updated
- 8 years ago
Overview
Brief Summary
The investigators will create a frailty index using health administrative data available for older people having surgery. The index will be based on the Canadian Study of Health and Aging Frailty Index and standard recommendations for creation of frailty indices.
Detailed Description
The investigators will create a frailty index using health administrative data available for older people having surgery. The index will be based on the Canadian Study of Health and Aging Frailty Index and standard recommendations for creation of frailty indices. Once derived the index will be tested to measure its association with outcomes, as well as its discrimination. Various representations of the frailty index will be tested (primary-as a continuous measure; secondary as a binary, categorical and fractional polynomial variable). Performance in subgroups will also be evaluated,
Investigators
Eligibility Criteria
Inclusion Criteria
- •Having elective or emergency noncardiac surgery
Exclusion Criteria
- •no provincial health insurance number
Outcomes
Primary Outcomes
Survival for One Year After Surgery
Time Frame: Date of surgery to 365 days after surgery
Still being alive (no death date) in the registered persons database Outcome is binary, exposure is per 0.1 unit increase
Secondary Outcomes
- Institutional Discharge(Date of surgery to date of hospital discharge, or up to one year after surgery (whichever comes first))