Comparison of ropivacaine (a local anaesthetic) and ropivacaine with fentanyl (an analgesic) injected adjacent to thoracic vertebra to provide pain relief in patients with multiple rib fractures
Phase 4
Completed
- Conditions
- Health Condition 1: null- Unilateral multiple rib fractures
- Registration Number
- CTRI/2012/12/003187
- Lead Sponsor
- niversity College of Medical Sciences and Guru Teg Bahadur Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 30
Inclusion Criteria
Patients having three or more unilateral fractured ribs
Exclusion Criteria
• Unconscious patients
• Patients with unstable cardiac status or severely altered mental status
• Known liver/kidney disease
• Known allergy to local anaesthetic drugs
• Infection at site of needle insertion
• Pre-existing spinal deformity
• Patients having significant trauma outside chest wall, e.g. acute spine or pelvic fracture, severe traumatic brain or spinal cord injury or abdominal visceral injuries
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Rescue analgesic (morphine) requirementTimepoint: Throughout study period till VAS score at rest and on coughing was not more than 10 to 15 mm for more than 8 hours
- Secondary Outcome Measures
Name Time Method â?¢ VAS pain scores at rest and on coughing <br/ ><br>â?¢ Respiratory rate <br/ ><br>â?¢ Peak expiratory flow rate <br/ ><br>â?¢ Arterial oxygen saturation (SpO2) <br/ ><br>â?¢ PaO2/FiO2 ratio <br/ ><br>Timepoint: Before administration of block, 30 min after block, every 6 hours on 1st day and then every 8 hours 2nd day onwards