Thoracic epidural anesthesia with ropivacaine: effects of age on neural blockade and cardiovascular parameters
Phase 4
Completed
- Conditions
- lokaal anestheticum gebruikt voor epidurale anesthesielung cancerpneumothorax
- Registration Number
- NL-OMON33234
- Lead Sponsor
- eids Universitair Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 75
Inclusion Criteria
male and female patients
ASA I-III
patients undergoing thoracic surgery under thoracic epidural anesthesia
Exclusion Criteria
Diabetes mellitus
Infection of the skin in the area of the epidural site
A history of neurological diseases
A history of bleeding diathesis
Muscle diseases
Hypersensitive to local anesthetics
Pregnancy or lactation
Participation in a trial on investigational drugs within 3 months prior to the study
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Neural blockade:<br /><br><br /><br>Time to initial onset of analgesia at the T3-T4 dermatomes<br /><br>Time to initial onset of motor blockade<br /><br>Time until maximum cephalad spread of analgesia<br /><br>Time until maximum caudad spread of analgesia<br /><br>Highest level of analgesia<br /><br>Maximum numbers of segments blocked<br /><br>Maximum score of motor block (Bromage scale and ESSAM score)<br /><br><br /><br>Cardiovascular:<br /><br><br /><br>Left ventricle systolic function<br /><br>Left ventricle diastolic function<br /><br>right ventricle systolic function</p><br>
- Secondary Outcome Measures
Name Time Method <p>not applicable</p><br>