Epidural anesthesia with ropivacaine and its effects in the duration of the muscular relaxation produced by rocuronium.

Not Applicable

• Conditions: Epidural Anesthesia; Neuromuscular Blockade; E03.155.197; E03.706

• Registration Number: RBR-7cyp6t
• Lead Sponsor: Faculdade de Ciências Médicas - Universidade Estadual de Campinas

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2018-08-17
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Data analysis completed
• Sex: Female
• Target Recruitment: Not specified

Inclusion Criteria

Elective Abdominal Surgeries performed under general anesthesia with or without association of epidural analgesia; female sex; age between 18 and 65 years old. Use of neuromuscular blocking agents; physical state ASA 1 and 2.

Exclusion Criteria

neuromuscular, renal and hepatic diseases; BMI greater than 32.5 or less than 20.0 kg.m-2; hydroelectrolytic and acid-base disorders; use of drugs that interact with neuromuscular blockers; contraindication to spinal blocks; history of hypersensitivity to drugs used

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Predicted outcome: A 20% time extension for recovery of a T4 / T1 ratio of 90% TOF = 0.9, assessed by monitoring neuromuscular block through peripheral nerve stimulator and thumb accelerometer measurement continuously evaluated throughout the operation, only after the intervention.;<br>Outcome found: there was no prolongation in time for recovery of a T4 / T1 ratio of 90% TOF = 0.9.

Secondary Outcome Measures

Name	Time	Method
Predicted outcome: A 20% time extension for the clinical duration, assessed by monitoring neuromuscular block through peripheral nerve stimulator and thumb accelerometer measurement continuously evaluated throughout the operation, only after the intervention.;Outcome found: there was no prolongation in clinical duration.