Effect of Nian-Mo granules for IgA nephropathy by regulating intestinal microecology
Phase 1
Recruiting
- Conditions
- IgA Nephropathy
- Registration Number
- ITMCTR2000004017
- Lead Sponsor
- Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
1. IgA nephropathy was confirmed by renal biopsy;
2. The glomerular filtration rate (eGFR) was more than 50 ml / min·1.73 m2;
3. Aged >= 18 years and <= 80 years, regardless of gender;
4. They agreed to participate in the study and signed informed consent.
Exclusion Criteria
1. Secondary IgAN, such as cirrhosis, lupus nephritis, hepatitis B associated nephritis, purpura nephritis, etc.;
2. Those who use steroid or immunosuppressant within 3 months;
3. No abnormality was found in stool microscopic examination, and no antibiotics or lactulose drugs affecting fecal pH value were used within 3 months before collecting fecal and blood samples;
4. Severe damage of heart, brain and liver function or other serious basic diseases.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method rine protein quantification;Microalbuminuria;renal function (Serum creatinine);
- Secondary Outcome Measures
Name Time Method Blood lipids (cholesterol, triglycerides, low density lipoprotein);Urinary N-acetyl-ß-D-glucosidase;routine urine test;Serum albumin;