Relationships of Executive Functions, Severity of Psychiatric Symptoms With Response to Therapy

Completed

• Conditions: Patient Acceptance of Health Care

• Registration Number: NCT04603170
• Lead Sponsor: Malahat Amani

Brief Summary

This study was conducted to investigate the moderating role of executive functions in the relationship between the severity of psychiatric symptoms and response to therapy. The statistical population of this study was all outpatients with anxiety disorders and depression who referred to psychiatric clinics.

Detailed Description

This study was conducted to investigate the moderating role of executive functions in the relationship between the severity of psychiatric symptoms and response to drug therapy in depressed and anxious patients. The statistical population of this study was all outpatients with anxiety disorders and depression who referred to psychiatric clinics. 164 participants completed Outcome Questionnaire, Brief Symptom Inventory, and Behavior Rating Inventory of Executive Function (BRIEF).

Study Timeline

• Study Start: 2019-01-01
• Primary Completion: 2019-02-01
• Study Completion: 2019-03-01
• Status Verified: 2020-10
• Study First Submitted: 2020-10-20
• Study First Submitted QC: 2020-10-20
• Study First Posted: 2020-10-26
• Last Update Submitted: 2020-10-26
• Last Update Posted: 2020-10-28

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 164

Inclusion Criteria

receiving a diagnosis of anxiety and depression disorders, age over 18 years, and taking drug medication prescribed by psychiatrists for at least one month.-

Exclusion Criteria

• having psychotic disorders, age under 18 years and absence from treatment.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Outcome questionnaire	ONE WEEK	This questionnaire was designed to assess response to treatment. This questionnaire has the dimension of mental distress or signs of distress, interpersonal relationships, and social role. This 45-item questionnaire is answered on a 5-point Likert scale ranging 0 to 4 (not at all to extremely).Scores range from 0 to180. higher scores mean a worse outcome.
Brief Symptom Inventory	ONE WEEK	This inventory measures the symptoms of psycho-somatization, obsessive-compulsive, interpersonal sensitivity, paranoid thoughts, depression, psychosis, general anxiety, hostility and anxiety. It was answered to questions based on the 5-point Likert scale ranging from 0 to 4 (not at all to perfectly). This questionnaire is 53 items. Scores range from 0 to 212.range of score are higher scores mean a worse outcome and mental health problems.
Behavior Rating Inventory of Executive Function	ONE WEEK	This questionnaire is used to measure the executive functions of adults aged 18 to 90 from their daily performance in the natural environment. It has 75 items that measure factors including response inhibition, shifting, emotional control, self-monitoring, initiation, working memory, planning, material organization, and task monitoring. It was answered to questions based on the 3-point Likert scale ranging from 0 to 2 (not at all to extremely). the scores range 0 to 150. High score is indicator of weak executive functions.

Trial Locations

Locations (1)

Malahat Amani; 🇮🇷 Bojnourd, North Khorsan, Iran, Islamic Republic of