Histologic and Histomorphometric Evaluation of Natix Synthetic Biomaterial in Horizontal Alveolar Ridge Augmentatio

Not Applicable

Conditions: Histologic and histomorphometric analysis of horizontal alveolar ridge augmentation.
Other disorders of teeth and supporting structures

Registration Number: IRCT138903164106N1

Lead Sponsor: Vice chancellor for research, Babol University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: All

Target Recruitment: 10

Inclusion Criteria

1- Patients ranging from 30 to 50 years old 2- Patients demanding implant treatment in posterior regions of mandibular alveolar ridge 3- Sufficient vertical height of bone in posterior mandibular region with inadequate buccolingual width (width of less than 5 mm and minimum width of 2 mm) 4- Healthy patients 5- Minimum of one augmentation site for each patient requiring implant treatment. Exclusion criteria: 1- Patients having systemic conditions affecting healing such as: Uncontrolled Diabetes, Immune diseases, Systemic or local diseases of bone, history of Alcoholism, Patients taking Immunosuppressive or Anticoagulant medications 2- poor compliance 3- Patients having untreated active periodontal disease 4- Patients unable to maintain oral health status or not interested in maintaining oral health status.

Exclusion Criteria

Not provided

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Histologic and Histomorphometric Evaluation of effect of Natix Synthetic Biomaterial in Horizontal Alveolar Ridge Augmentation. Timepoint: 8 months after intervention. Method of measurement: Biopsy specimens are taken from the augmented site by Natix, and are stained with Hematoxilin & Eosin and parameters such as: 1-amount of inflammation 2-existence or inexistence of foreign body reaction (giant cells and granulomatous reactions) 3-Bone vitality (Existence or inexistence of osteocytes in lacunaes) 4-Thickness of bone trabecules 5-Way of contact between bone-biomaterial (existence or inexistence of connective tissue between bone fragments) are analysed.

Secondary Outcome Measures