Histomorphometric and histopathologic findings in patients undergoing left atrial appendage closure with use of a double-filter embolic protection device

Recruiting

• Conditions: Percutaneous-transluminal vascular intervention on heart and coronary vessels: Measures for embolism protection on the left heart ear: Implantation of a permanent embolism protection systemTransseptal left heart catheter examination: pressure measurementTransesophageal Echocardiography [TEE]; I63; Atrial fibrillation and flutter; Cerebral infarction; I48

• Registration Number: DRKS00022411
• Lead Sponsor: Klinikum Friedrichshafen GmbH Klinik für Kardiologie, Angiologie, Pneumologie und Internistische Intensivmedizin

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2020-09-15
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

>18 years
written, informed consent
signed transfer agreement for tissue samples

Exclusion Criteria

Age <18 years
no indication for LAA

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
How often in patients with an LAA is material used in the<br>both filters of the dual filter protection system?<br>Which material (thrombus, myocardium, calcium, foreign body) is found in these filters?<br>

Secondary Outcome Measures

Name	Time	Method
What is the number and size of the collected particles?<br>Is there an association between device size selection or procedural data (periprocedural blood dilution, blood pressure) in relation to the number and Scope of the collected material?