跳至主要内容
临床试验/NCT00368524
NCT00368524已完成不适用

Cost Effective Treatment for Dually Diagnosed Homeless

University of Alabama at Birmingham0 个研究点目标入组 160 人开始时间: 2001年11月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
160
主要终点
abused drug abstinence measured by observed urine specimen testing weeks 1-52, and bimonthly months 13-18

研究概览

简要总结

This randomized controlled trial examined whether an abbreviated treatment using abstinence contingency management for housing and work/training (CM, n=103) with cocaine dependent, non-psychotic, dually diagnosed homeless persons, would show non-inferior outcomes compared to the full treatment (CM+, n=103). It was hypothesized that CM+ would show superior abstinence and retention outcomes, but that CM, with components derived from previously effective behavioral day treatment, would obtain non-inferior outcomes, defined as 75% or more of those observed for the full treatment (CM+) during active treatment months 1-6. The CM+ included all CM components but added behavioral day treatment that included voucher reinforcement of $7.50-15.00, for objective weekly therapeutic goal attainment in five domains of functioning: drug dependence, homelessness, unemployment, non-drug related recreational activities, and behavioral, health, or mental health problems. Abstinence was assessed by observed urine specimen collection and weekly testing weeks 1-52, and randomly, bi-monthly for months 13-18. Abstinence, homelessness, employment and other outcomes were also assessed at baseline, 2, 6, 12, and 18 months.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Single

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • McKinney Act criteria for homelessness; DSM IV diagnosis for Cocaine Dependence; self-reported use within the last 2 weeks; psychological distress indicated by score of 70 on 1 or more Brief Symptom Inventory scales; willingness to participate; no plans to move from Birmingham area for 18 months;

排除标准

  • cognitive impariment precluding informed consent; requiring immediate inpatient medical treatment

结局指标

主要结局

abused drug abstinence measured by observed urine specimen testing weeks 1-52, and bimonthly months 13-18

次要结局

  • abstinence, housing, employment and other outcomes at 0, 2, 6, 12 and 18 months.

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Penelope Baker Jester

Principal Investigator

University of Alabama at Birmingham

相似试验