on-surgical treatment of peri-implantitis, a randomized, single blind, controlled trial

Phase 4

Completed

• Conditions: Inflammation of the supporting tissues around a dental implant; 10004018; infectious disease of the tissues around a dental implant

• Registration Number: NL-OMON41564
• Lead Sponsor: Vrije Universiteit

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 48

Inclusion Criteria

Dentate or edentate patients with at least one screw-type titanium implant;The implant should be in function for at least a period of 12 months;Peri-implant intraosseous defect with at least 3 mm depth measured from the neck. The extent of bone loss will be measured on the basis of peri-apical radiographs;Probing depth at the deepest site at least 5mm combined with bleeding and/or suppuration;Patient above 18 years of age;Psychological appropriateness;Signed Informed Consent obtained prior to start

Exclusion Criteria

Patient with a history of taking systemic antibiotics in the preceding 3 months;Patient allergic to penicillin (amoxicillin) or metronidazole ;Systemic diseases like diabetes, HIV, Sjögren, SLE;Use of NSAID*s in the last 4 weeks;Current pregnancy or lactating;Mobile implants

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main outcome is the clinical attachment level (CAL). </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Clinical parameters (pocket probing depth (PPD), bleeding on probing (BoP),<br /><br>plaque-accumulation and bone loss) and microbiological parameters. </p><br>