Repeated non-surgical periimplantitis therapy with two different antiseptic adjuncts. A randomized controlled clinical trial.
Phase 4
Recruiting
- Conditions
- peri-implantitis (inflammation with bone affection)
- Registration Number
- DRKS00007911
- Lead Sponsor
- Zentrum für Zahnmedizin. Klinik für Präventivzahnmedizin, Parodontologie und Kariologie
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
• Informed Consent as documented by signature
• Systemically healthy subjects
• At least one dental implant with periimplantitis in terms of a progressive bone loss, probing pocket depth of = 6 mm and bleeding on probing and a vertical
bone loss of max. 5 mm.
• Fixed prosthetics
Exclusion Criteria
• Patients with untreated periodontitis
• Heavy smokers (> 20 cigarettes)
• Pregnant or nursing women.
• Patients with antibiotic therapy within the last 6 months
• Patients with periimplantitis therapy within the last 3 months
• Subjects with an allergy to either PVP-iodine or chlorhexidine
• Anti-coagulated patients (exception: intake of 100 mg acetylsalicyl acid per day)
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Primary outcome variable is the periimplant pocket depth in combination with bleeding-on-probing 24 weeks after baseline examination.
- Secondary Outcome Measures
Name Time Method Secondary outcomes are the change in plaque accumulation (Plaque index), radiographic bone level and the taxa of key bacteria species 2, 4, 6, 9, 12 and 24 weeks after baseline examination.