MedPath

Treatment of peri-implant mucositis with repeated application of chlorhexidine chips or gel during supportive therapy – a randomized clinical trial

Not Applicable
Conditions
M27.62 (ICD 10 CM) Post-osseointegration biological failure of dental implant
Registration Number
DRKS00017782
Lead Sponsor
Clinic of Preventive Dentistry, Periodontology and Cariology
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
40
Inclusion Criteria

• Adult women and men (=18 y)
• Informed consent as documented by signature
• Systemically healthy subjects
• At least one dental implant loaded by fixed single crowns or bridges (screwed or cemented) with mucositis in terms of a probing pocket depth between 3 an 5 and bleeding on probing
• Bone loss = 2mm as detectable on X-ray
• Ability to read and understand the patient information

Exclusion Criteria

• Patients with active periodontal pockets
• Pregnant or nursing women or women planning to have a child
• Patients with antibiotic therapy within the previous 6 months
• Patients with peri-implantitis therapy within the previous 3 months
• Subjects with an allergy to CHX
• Heavy smokers (=10 cigarettes per day)
• Anti-coagulated patients (exception: =100 mg/d acetylsalicylic acid)
• Removable prostheses attached on the affected implants

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Manual assessment of peri-implant pocket depths with a periodontal probe after 6 months
Secondary Outcome Measures
NameTimeMethod
Assessemnt of bleeding-on-probing and aMMP-8 levels after 6 months
© Copyright 2025. All Rights Reserved by MedPath