QUO VADIS - QUality Of Life and surviVAl in carDIac arreSt Patients
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 1,600
- 主要终点
- Neurological Outcome
研究概览
简要总结
QUO VADIS is a national observational study with the aim to describe clinical intervention and utilization of neuroprognostication tools in the management of patients admitted to ICU following cardiac arrest
详细描述
Despite recent improvements in post-resuscitation care, about 50% of patients resuscitated from cardiac arrest die or have poor neurological prognosis. Post-anoxic brain injury is common after cardiac arrest and is a major cause of post-resuscitation mortality. Since there has been a significant investment in improving the emergency response to both in-hospital ad out-of-hospital cardiac arrest (IHCA and OHCA, respectevly) patients and reported improvements in short-term survival outcomes, the long-term neurological state and quality of life of survivors and their caregiver is of growing significance.
QUO VADIS is a national observational study created to describe clinical interventions and utilization of neuroprognostication tools in the management of patients admitted to ICU following cardiac arrest.
The aims of the study are:
- To create an Italian Registry that describes clinical interventions and neuroprognostication tools used in the management of patients admitted to ICU following cardiac arrest
- To evaluate, after one year from the cardiac arrest, the neurological outcome and the quality of life of the patients;
- To evaluate, after one year from the cardiac arrest, the quality of life of caregivers;
- To identify the most effective clinical intervention in the management of post-cardiac arrest patients admitted to ICU;
- To create a prognostic model for patients admitted to ICU after cardiac arrest.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 14 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age ≥ 14 years;
- •Cardiac Arrest within 24 hours ICU admission
排除标准
- •Absence of Informed consent;
- •Age < 14 years
结局指标
主要结局
Neurological Outcome
时间窗: 6 months
mRS (modified Ranking Scale) Minimum value: 0 = Complete recovery; Maximum value: 6 = Death
Patients quality of life
时间窗: 12 months
EuroQoL-5D (european quality of life 5 dimensions). 0 = Worst imaginable health state; 100 = best imaginable health state
Disability
时间窗: 6 months
GOSe (Glascow Outcome Scale extended). Minimum value: 1 = Dead; Maximum value: 8= Upper Good Recovery
次要结局
- Caregiver quality of life(12 months)