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Preliminary Efficacy of Occupational Therapy Integrating Horses on Self-regulation in Youth With Autism

Not Applicable
Recruiting
Conditions
Autism Spectrum Disorder
Interventions
Behavioral: OTEE HORS
Behavioral: OT Clinic
Registration Number
NCT05846932
Lead Sponsor
Colorado State University
Brief Summary

The goal of this clinical trial is to learn about occupational therapy integrating horses for autistic youth. The main questions it aims to answer are:

* Does occupational therapy integrating horses improve self-regulation in autistic youth

* Does occupational therapy integrating horses affect salivary cortisol and alpha-amylase

Participants will receive 10 weeks of occupational therapy, and will be asked to provide saliva samples each week.

Researchers will compare occupational therapy integrating horses to occupational therapy in a clinic to see if integrating horses affects self-regulation.

Detailed Description

The goal of this project is to quantify the unique benefits of integrating horses in occupational therapy compared to occupational therapy in a clinic (i.e., OTEE HORS vs. OT Clinic) for improving self-regulation in youth with ASD.

To address both aims we will randomize 64 youth with ASD ages 6-11 years old to OTEE HORS or OT clinic.

Specific Aim 1: Examine the preliminary efficacy of OTEE HORS compared to OT Clinic on self-regulation. Hypotheses: The OTEE HORS group will demonstrate significantly larger improvements than the OT Clinic group in five domains of self-regulation (hyperactivity \[primary\], irritability, emotional reactivity, dysphoria, and individual goal attainment).

Specific Aim 2: Identify potential physiological mechanisms that explain how integration of horses in occupational therapy impacts self-regulation in youth with ASD. Hypotheses 2A \& B: The OTEE HORS group will demonstrate significantly larger decreases in salivary cortisol after each 60-minute therapy session and after the 10-week treatment course in comparison to the OT Clinic group. Hypotheses 2C \& 2D: The OTEE HORS group will demonstrate significantly greater increases in salivary alpha-amylase after each 60-minute therapy session, and significantly greater decreases in salivary alpha-amylase over time as measured after the 10-week treatment course in comparison to the OT Clinic group. Exploratory Hypothesis 2E: Changes in physiological measures will significantly correlate with changes in Aim 1 behavioral measures.

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
64
Inclusion Criteria
  • meet clinical cut-offs for ASD on the Autism Diagnostic Observation Schedule, Second Edition(ADOS-2) and Social Communication Questionnaire (≥ 11)
  • nonverbal IQ≥65 on Leiter International Performance Scale Third Edition (Leiter-3)
  • verbally fluent defined by meeting standard administration criteria for ADOS-2 module 3
  • score >10 on the irritability subscale of the aberrant behavior checklist
  • able to tolerate a helmet and ride a horse for 10 minutes while following safety rules
  • and able to provide a saliva sample
Exclusion Criteria
  • weigh more than 200 pounds
  • smoke or regularly use steroids
  • receive outpatient occupational therapy
  • have 10+ hours horseback riding experience in the previous 6 months
  • history of animal abuse or phobia of horses
  • have a sibling previously enrolled in the study

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Occupational Therapy Integrating HorsesOTEE HORS10 weeks of occupational therapy focused on self-regulation skills, provided while participants are riding horses
Occupational Therapy in a ClinicOT Clinic10 weeks of occupational therapy focused on self-regulation skills, provided in a traditional clinic environment
Primary Outcome Measures
NameTimeMethod
Change in Aberrant Behavior Checklist, CommunityWeek 1 & Week 10

Parent-report checklist of problematic behaviors related to hyperactivity and irritability

Secondary Outcome Measures
NameTimeMethod
Change in Concentration of Salivary CortisolWeek 1, Week 6, Week 10
Change in Emotional Dysregulation InventoryWeek 1 & Week 10

Parent-report measure of emotional reactivity and dysphoria

Change in Concentration of Salivary Alpha-amylaseWeek 1, Week 6, Week 10
Goal Attainment using Goal Attainment ScaleWeek 10

Attainment of individualized self-regulation goals. Goal attainment scales range from -2 to +2 where higher values indicate greater progress towards individual goal.

Trial Locations

Locations (1)

Temple Grandin Equine Center

🇺🇸

Denver, Colorado, United States

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