Contribution of the ENT (Ear, Nose, and Throat) Surgeon's Clinical Evaluation to the Contouring of Target Volumes and Organs Eligible for Radiotherapy in Head and Neck Cancers

Completed

• Conditions: Surgeons; Radiotherapy, Conformal (IMRT); Head and Neck Cancer; Otolaryngology; Radiation Oncologists

• Registration Number: NCT03265873
• Lead Sponsor: Fondation Ophtalmologique Adolphe de Rothschild

Brief Summary

Radiotherapy (RT), surgery and chemotherapy (CT) are treatments for head and neck cancers, used alone or in combination. Conformal RT with Intensity Modulation (IMRT) is currently the reference technique. IMRT requires a precise definition of the target volumes to be treated and the anatomical structures to be protected from irradiation. Most studies of head and neck cancers published in the literature demonstrate the variability in the contouring of the target volumes between radiotherapists. This may have an impact on dosimetry. To date, no studies have evaluated the impact of the ENT surgeon's evaluation in volumes contouring. The aim of this study is to compare the volumes determined by the radiotherapists alone and those determined jointly by the radiotherapists and the ENT surgeon.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2017-08-28
• Study First Submitted QC: 2017-08-28
• Study First Posted: 2017-08-29
• Study Start: 2017-11-28
• Status Verified: 2023-10
• Primary Completion: 2023-10-13
• Study Completion: 2023-10-13
• Last Update Submitted: 2023-10-25
• Last Update Posted: 2023-10-26

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• Age ≥ 18 years;
• Cancer of the upper aerodigestive tract (oral cavity, oropharynx, larynx, hypopharynx, rhinopharynx, salivary glands, facial sinuses, orbital cavity, ear);
• Cancer confirmed by histopathological analysis;
• Therapeutic protocol including radiotherapy.

Exclusion Criteria

• Any history of radiotherapy of the head and neck
• Synchronous head and neck cancer.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Proportion of patients with head and neck cancer for whom a change in the CTV (Clinical Target Volume) was made following the advice of the ENT surgeon.	Baseline

Trial Locations

Locations (2)

Fondation Ophtalmologique A. de Rothschild; 🇫🇷 Paris, France

Hôpital d'Instruction des Armées; 🇫🇷 Clamart, France