Inherited Thromophilia and Thrombotic Risks in Inflammatory Bowel Disease During Activity and Remission

Not yet recruiting

• Conditions: Inflammatory Bowel Diseases

• Registration Number: NCT06691451
• Lead Sponsor: Asmaa mohammed abdelaal abdelaal

Brief Summary

Inherited thombopllia and thrombotic risks in inflammatory bowel Disease during activity and remission

Detailed Description

Inflammatory bowel diseases (IBD) are systemic conditions characterized by multiple intestinal and extra-intestinal manifestations related to the associated chronic inflammatory state. Among their diverse extra-intestinal complications, venous thromboembolism (VTE) remains one of the most under recognized causes of morbidity and mortality in these patients, highlighting the need for a better understanding of the underlying mechanism of hypercoagulability, in addition to the role of acquired and inherited risk factors that further increase the risk of thrombosis with its impact on patients' outcomes.\[1, 2\]

Study Timeline

• Status Verified: 2024-11
• Study Start: 2024-11
• Study First Submitted: 2024-11-14
• Study First Submitted QC: 2024-11-14
• Last Update Submitted: 2024-11-14
• Study First Posted: 2024-11-15
• Last Update Posted: 2024-11-15
• Primary Completion: 2026-12
• Study Completion: 2027-03

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 93

Inclusion Criteria

• Age (18yrs - 65yrs) both sex

Exclusion Criteria

• Presence of acquired cause (pregnancy, recent surgery, history of drug, History of malignant Disease, History of blood or blood product transfusion in last 4 weeks)

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Comparison between the number of IBD patients with tendency to thrombosis in cases of activity-	Baseline	-investigate the presence of multiple mutations associated with IBD patients with or without vascular complications.