Assessment of implication of Massive Transfusion Guidelines in conjunction with incidence of coagulopathy and outcome in the Northern Tasmania

Not Applicable

Completed

• Conditions: Massive bleeding defined by the replacement of one blood volume in a period of 24 hrs or replacement of 50% of the total blood volume within three hours, or a rate of loss of 150 ml/hr, which is more relevant in the acute clinical setting.; Blood - Haematological diseases; Blood - Clotting disorders

• Registration Number: ACTRN12611001258943
• Lead Sponsor: none

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2011-12-07
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

Patients from both sexes who presents with masive bleeding during the study period and who required MTP defined by transfusion of whole blood volume within 24 hours or replacement of half blood volume within 4 hours with ongoing need for transfusion.

Exclusion Criteria

Patients who are not considered as per definition as massive transfusion

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Assessment of outcome of use of MTP in a single institution since 2007.<br>Tools/methods: Full blood count (FBC), Coagulation parameters; use of different blood products and outcome of MTP.[Will be assessed by the end of study.]

Secondary Outcome Measures

Name	Time	Method
Assessment of the incidence Disseminated intravascular coagulation (DIC).<br>Tools: Coagulation parameters such as APTT, PT, Fibrinogen and Di Dimer; use of different coagulation factors such as FFP, Cryopricipitate and others (ativated factor VIIa, prothrombin complex etc..).[Will be assessed by the end of study.]