To observe the additional pain sparing effect of the drug (dexamethasone)in addition to primary drug (levobupivacaine or ropivacaine )given as injection in between two muscles in patients who undergo breast cancer surgey.
Phase 4
Completed
- Conditions
- Health Condition 1: C509- Malignant neoplasm of breast of unspecified site
- Registration Number
- CTRI/2020/03/024149
- Lead Sponsor
- Department of anesthesia and intensive care government medical college and hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
females suffering from carcinoma breast.
American Society of Anaesthesiologists (ASA) physical status I ââ?¬â??II.
Age ranging from 18-80 years.
Exclusion Criteria
Patient refusal.
History of relevant drug allergy.
History of psychiatric illness and substance abuse.
Patient suffering from severe cardiovascular, respiratory, liver, metabolic or neurological disease.
Chronic treatment with analgesics.
Pregnant patient.
Coagulopathy.
Infection at planned injection site. Psychological inability of patient to understand.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Time to first rescue analgesic and <br/ ><br>Cumulative morphine consumption over 24 <br/ ><br>hours in patients receiving SAM block with levobupivacaine or ropivacaine . <br/ ><br>Timepoint: post operative at 30min , 1hr , 4hrs, 8hrs,12hrs and 24hrs
- Secondary Outcome Measures
Name Time Method 1.Reduction in pain intensity by VAS score. <br/ ><br>2.Total dose of anti-emetics over 24hrs. <br/ ><br>3.Any side effects pertaining to the procedureTimepoint: Post-operative at 30mins,1hr,4hrs,8hrs,12hrs <br/ ><br>and 24hrs. <br/ ><br>2.Post-operative at 30mins,1hr,4hrs,8hrs,12hrs <br/ ><br>and 24hrs <br/ ><br>3.Post-operative at 30mins,1hr,4hrs,8hrs,12hrs <br/ ><br>24hrs.