The effect of the combination of Ketamine and Midazolam as well as a combination of ketamine and dexmedetomidine in Electroshock therapy
Phase 2
Recruiting
- Conditions
- ElectroConvulsive Therapy.
- Registration Number
- IRCT20160307026950N23
- Lead Sponsor
- Esfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 70
Inclusion Criteria
Candidate patients for Electroconvulsive Therapy
Age 18 to 65
Patient consent to study
Exclusion Criteria
History of drug allergy
History of cardiovascular disease
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Heart Rate. Timepoint: Before drug injection, after drug injection, after shock termination, 5 and 10 minutes after end of seizure. Method of measurement: ECG monitoring.;Blood Pressure. Timepoint: Before drug injection, after drug injection, after shock termination, 5 and 10 minutes after end of seizure. Method of measurement: Non-invasive blood pressure measurement.;Oxygen Saturation. Timepoint: Before drug injection, after drug injection, after shock termination, 5 and 10 minutes after end of seizure. Method of measurement: Pulse Oxymeter.
- Secondary Outcome Measures
Name Time Method Duration of seizures. Timepoint: From the beginning to the end of the seizure. Method of measurement: Chronometer.;Complications after anesthesia. Timepoint: From the time of drug discontinuation to the end of recovery. Method of measurement: View patient status.;Recovery time. Timepoint: From stopping the drug to full consciousness. Method of measurement: Chronometer.