The effect of drug oral Ibandronate sodium 150mg in patients with bone disease with missing teeth requiring dental implants.

Not Applicable

• Conditions: Health Condition 1: null- 1.Implants in Normal health individuals 2.Implants in proved osteoporotic on calcium and vitamin supplements only.3.Implants in osteoporotic cases with supplement of Ibandronate sodium 150 mg

• Registration Number: CTRI/2018/01/011420
• Lead Sponsor: Vishnu Dental College

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

a.History of extraction /tooth loss more than 3 months.

b.Normal healthy patients above 40 years indicated for extraction with subsequent dental implants.

c.Patients with osteoporosis indicated for oral rehabilitation with dental implants.

d.Patients who are advised for full mouth extraction planned for implant prosthesis.

e.Partially, completely edentulous patients reporting for the requirement of implant prosthesis.

f.Osteoporosis patients under calcium and vitamin-D supplementation other than bisphosphonates

Exclusion Criteria

a.Patients on long term corticosteroid therapy.

b.Patients with history of liver disease.

c.Patients with history of diabetes mellitus.

d.Patients with other debilitated disease.

e.Patientâ??s with autoimmune diseases

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1)confidence interval-95% <br/ ><br>2)power of study-80% <br/ ><br>which means that maximum acceptable Type I errors and TypeII errors are 5 and 20 respectively. <br/ ><br>A)Positive results may be achieved with this study by the oral use of the drug Ibandronate sodium 150mg that can minimize the alveolar resorption around dental implants which might enhance early oral rehabilitation and improve ridge remodeling in implant surgery.Timepoint: within 3 years of time period

Secondary Outcome Measures

Name	Time	Method
A)establish early osseointegration,early rehabilitation in osteoporotic patients by using the drug Ibandronate sodium orally to hinder resorption. <br/ ><br>achieve sustenance of good bone around dental implants and to design a protocol for the management of alveolar resorption in osteoporotic cases requiring Dental implants.Timepoint: with in 3 years of time period